Comprehensively explores sexually transmitted diseases, from epidemiology, causative pathogens, clinical impact, and immunology, to management strategies utilizing new strategies of genomics and next-generation diagnostic tools Sexually transmitted infections (STI) are very common worldwide. More than 20 different STIs have been identified, and about 19 million men and women are infected each year in the United States alone. This book looks at the complete picture of common STIs— how they form, evolve, and transmit, as well as how they can be treated and managed with modern techniques, medicines, and tools. Diagnostics to Pathogenomics of Sexually Transmitted Infections runs the spectrum of discussion ranging from introduction of causative pathogen, their pathogenesis to epidemiology, immunology, to anatomy and physiology of human genitalia and management strategies. The book offers in-depth chapter coverage on effect of probiotics on reproductive health; mucosal immunity in sexually transmitted infections; the role of circumcision in preventing STIs; Human Immunodeficiency Virus (HIV); genital herpes; molluscum contagiosum; genital warts; chlaymydia trachomatis; donovanosis; gonorrhoea; treponematoses; genital mycoplasms; bacterial vaginosis; vulvovaginal candidiasis; chlaymydia; scabies; chancroid, yeast infections; and more. Comprehensively compiles most of the major sexually transmitted infections Presents updated information on clinical aspects of sexually transmitted infections Examines the priorities in pathogenesis of human sexually transmitted infections and discusses new strategies of genomics and next-generation diagnostic tools used for detection of such pathogens Explores the future of rapid molecular diagnostic techniques and the challenges posed in the diagnosis of human STIs Includes bench to bedside content that will appeal to both basic and clinical researchers By offering the latest knowledge about recent advances in sexually transmitted infections in an interdisciplinary fashion, Diagnostics to Pathogenomics of Sexually Transmitted Infections is the perfect book for virologists, microbiologists, infectious disease experts, vaccinologists, biomedical researchers, clinicians, pharmacologists, and public health specialists.
AIDS is a contagious disease, currently incurable. Dozens of millions of HIV-positive are already registered worldwide, and each year this number grows. In recent years, AIDS/HIV became a major problem both for people from «risk groups», and for ordinary people. The book gives a number of important recommendations on how to suppress further expansion of this dangerous disease.
Praise for Handbook of HIV and Social Work «Cynthia Cannon Poindexter has given us a remarkable edited volume that contains much information on HIV that every professional social worker needs to know in order to practice competently in today's complex world.»—From the Foreword by Vincent J. Lynch, MSW, PhD, Boston College Graduate School of Social Work «This comprehensive handbook assembles a group of social work scholars and practitioners to participate in, guide, and address many of the unresolved challenges characterizing the HIV debates. This handbook is a valuable and timely addition to the literature.»—King Davis, MSW, PhD, The Robert Lee Sutherland Chair in Mental Health and Social Policy, The University of Texas at Austin School of Social Work «This handbook is an outstanding resource for the social work professional working to ensure equal access to care, treatment, and resources for all persons living with and/or affected by HIV.»—Evelyn P. Tomaszewski, MSW, Project Director, NASW HIV/AIDS Spectrum: Mental Health Training and Education of Social Workers Project «This book is an excellent, up-to-date guide on HIV. It is an indispensable resource for all those who work with HIV and all its complications.»—Leon Ginsberg, MSW, PhD, Dean Emeritus, University of South Carolina School of Social Work and Editor, Administration in Social Work The most current knowledge on the HIV pandemic in a thorough, diverse, and accessible volume This invaluable book draws on a distinguished roster of HIV advocates, educators, case managers, counselors, and administrators, assembling the most current knowledge into this volume. Handbook of HIV and Social Work reflects the latest research and its impact on policy and practice realities, with topics including: History, Illness, Transmission, and Treatment Social Work Roles, Tasks, and Challenges in Health Care Settings HIV-related Community Organizing and Grassroots Advocacy The Impact of HIV on Children and Adolescents HIV-affected Caregivers
Today over 40 million adults and children worldwide are infected with HIV, however knowledge of the disease has increased greatly and the prognosis is now good for those with access to anti-retroviral treatment. For many, HIV is now a long-term chronic condition and with decreased mortality, patient requirements and disease patterns have changed, making it increasingly apparent to health care professionals that the treatment of HIV should include optimum nutrition and healthy lifestyle interventions to help sufferers lead long and healthy lives. In this essential new book an international team of authors under the editorship of Specialist HIV Dietitian Vivian Pribram bring together the latest research to provide the practicing dietitian and nutritionist with a practical guide to the nutritional care of the HIV and AIDS patient. Students and other health care professionals working and studying this area will also find Nutrition and HIV an important and valuable resource.
Histologic Basis of Ocular Disease in Animals is a comprehensive reference covering pathology of the eye in a spectrum of animal species, including domestic animals, fish, birds, and laboratory animals. Offers a comprehensive resource on diseases and conditions of the eye and orbit in a wide range of species Covers domestic animals, fish, birds, and laboratory animals Presents more than 1200 high-quality images carefully selected to illustrate the ocular conditions covered Emphasizes unique pathological responses where necessary
A detailed look at the latest research in non-invasive in vivo cytometry and its applications, with particular emphasis on novel biophotonic methods, disease diagnosis, and monitoring of disease treatment at single cell level in stationary and flow conditions. This book thus covers the spectrum ranging from fundamental interactions between light, cells, vascular tissue, and cell labeling particles, to strategies and opportunities for preclinical and clinical research. General topics include light scattering by cells, fast video microscopy, polarization, laser-scanning, fluorescence, Raman, multi-photon, photothermal, and photoacoustic methods for cellular diagnostics and monitoring of disease treatment in living organisms. Also presented are discussions of advanced methods and techniques of classical flow cytometry.
With 40% new material the new edition of Advanced Wireless Networks provides a comprehensive representation of the key issues in 4G wireless networks. Focussing on cognitive, cooperative and opportunistic paradigms to provide further increase in network efficiency, the book explores and addresses issues in wireless internet, mobile cellular and WLAN, as well as sensor, ad hoc, bio-inspired, active and cognitive networks. It examines the problem of cross-layer optimisation and network information theory as well as adaptability and reconfigurability in wireless networks. This book is an integral description of future wireless networks and the interconnection between their elements. The information is presented in a logical order within each chapter making it ideal for all levels of reader including researchers involved in modelling and analysis of future networks as well as engineers working in the area. Each chapter starts with introductory material and gradually includes more sophisticated models and mathematical tools concluding with a comprehensive list of references. Fully updated throughout with five new chapters on Opportunistic Communications; Relaying and Mesh Networks; Topology Control; Network Optimization; and Cognitive Radio Resource Management Unifies the latest research on cognitive, cooperative and opportunistic paradigms in wireless communications Provides efficient analytical tools for network analysis Discusses security issues, an essential element of working with wireless networks Supports advanced university and training courses in the field Companion website containing extra appendix on Queuing theory
Emerging Infectious Diseases offers an introduction to emerging and reemerging infectious disease, focusing on significant illnesses found in various regions of the world. Many of these diseases strike tropical regions or developing countries with particular virulence, others are found in temperate or developed areas, and still other microbes and infections are more indiscriminate. This volume includes information on the underlying mechanisms of microbial emergence, the technology used to detect them, and the strategies available to contain them. The author describes the diseases and their causative agents that are major factors in the health of populations the world over. The book contains up-to-date selections from infectious disease journals as well as information from the Centers for Disease Control and Prevention, the World Health Organization, MedLine Plus, and the American Society for Microbiology. Perfect for students or those new to the field, the book contains Summary Overviews (thumbnail sketches of the basic information about the microbe and the associated disease under examination), Review Questions (testing students' knowledge of the material), and Topics for Further Discussion (encouraging a wider conversation on the implications of the disease and challenging students to think creatively to develop new solutions). This important volume provides broad coverage of a variety of emerging infectious diseases, of which most are directly important to health practitioners in the United States.
An authoritative look at the application of chemical biology in drug discovery and development Based on the award-winning Wiley Encyclopedia of Chemical Biology published in 2008, this book explores the role of chemical biology in drug discovery and development. The first part of the book reviews key principles and techniques used in the design and evaluation of drug candidates. The second part elucidates biological mechanisms of certain diseases, illuminating approaches to investigate and target these diseases. Comprising carefully selected reprints from the Encyclopedia as well as new contributions from leading scholars in the field, this book provides researchers in academia and industry with important information to aid in the development of novel agents to treat disease. Self-contained articles cover a variety of essential topics, including: The design, development, and optimization of drug candidates The pharmacokinetics and properties of drugs Drug transport and delivery Natural products and natural product models as pharmaceuticals Biological mechanisms underlying health and disease Treatment strategies for a range of diseases, from HIV to schizophrenia Chemical Biology is a top-notch guide and reference for anyone working in the areas of drug discovery and development, including researchers in chemical biology and other fields such as biochemistry, medicine, and pharmaceutical sciences.
With sexually transmitted infections (STIs) a major cause of morbidity and mortality throughout the world, the new edition of ABC of Sexually Transmitted Infections is a much-needed introduction and reference guide providing concise and practical information on a range of conditions. This sixth edition includes the latest guidance on the prevalence, prevention and treatment of STIs, screening programmes and new testing methods. It features new chapters on service modernisation and new care providers, high risk and special needs groups, the use of the internet for information and education, systemic manifestations and sexually transmitted infections in resource-poor settings. Contraception is also covered, reflecting the increasing integration of STI and contraceptive services. With an international authorship, the ABC of Sexually Transmitted Infections is an authoritative guide and reference for all practitioners, especially those providing community based STI diagnosis and management such as GPs, primary care physicians and contraceptive service providers. Junior doctors, medical students, and nurses working in community or specialist services will also find it a valuable resource as will those working in the fields of obstetrics and gynaecology and public health. This new edition also provides information useful for new STI care providers such as pharmacists, those in the voluntary sector and providers of STI services in resource-poor settings.
BACE inhibitors and their use in the treatment of Alzheimer's Disease BACE (β-site of APP cleaving enzyme) is a critical component in Alzheimer's Disease (AD), and the development of BACE inhibitors shows great potential as a therapy for the disease. BACE: Lead Target for Orchestrated Therapy of Alzheimer's Disease covers virtually all aspects of BACE from initial identification, discovery of inhibitors, and challenges in clinical development, while providing a global understanding essential for productive and successful drug discovery. This book details the story of the discovery of BACE and its role in AD and comprehensively discusses: The development of BACE inhibitors as therapeutics for Alzheimer's disease The research that led to the identification of BACE New BACE inhibitors currently being clinically tested ADME (absorption, distribution, metabolism, excretion) and clinical trial design—topics not addressed in current field literature Cutting-edge technology such as high-throughput screening, structure-based drug design, and QSAR in context of BACE inhibitors and Alzheimer's drug discovery Other approaches to BACE inhibition based on interaction with the precursor protein APP By enhancing the reader's understanding of the various aspects of the BACE drug-discovery process, this much-needed reference will serve as a key resource for all scientists involved in Alzheimer's research—and inspire new approaches to treatment of AD.
Pediatric respiratory disorders are responsible for a number of acute and chronic health conditions and are a leading cause of pediatric emergency room visits and hospitalizations. More than ever, nurses and nurse practitioners must have an understanding of the anatomy, pathophysiology, diagnosis and state of the art treatments in pediatric respiratory disease as they are often the first to come in contact with and recognize respiratory problems in children. Nursing Care in Pediatric Respiratory Disease seeks to provide both nurses and nurse practitioners with this information in order to aid them in the diagnosis and treatment of children suffering from acute and chronic respiratory disorders. Nursing Care in Pediatric Respiratory Disease opens with an overview of the anatomy and physiology of the respiratory system, best practices for assessing respiratory symptoms in children, and common respiratory therapies and treatment methods. It then proceeds through an examination of varying acute and chronic upper and lower respiratory diseases spanning from asthma and cystic fibrosis to vocal cord paralysis and sinusitis in both hospital and ambulatory settings. Nursing Care in Pediatric Respiratory Disease provides nurses and other health care providers with a comprehensive and practical resource which allows them to collaborate and advocate more effectively, as well as educate both the family and child in management of respiratory disorders.