Fusing aesthetic and economic analyses, Embroidering Lives investigates the lives and work of women in the chikan embroidery industry of Lucknow, India. Richly descriptive and accessibly written, the book explores many important issues in women's studies, anthropology, and urban development today - the impact of purdah (seclusion of women) upon women's work and occupational opportunities, the key role of sub-contractors in home-based industry, the need to understand a handicraft from its makers' point of view, and the role of development agencies and programs.
The Definitive reference on the important role fathers play in child development today Edited by Dr. Michael Lamb—the recognized authority on the role of fathers in child development, The Role of the Father in Child Development, Fifth Edition brings together contributions from international experts on each subject to provide a thorough and current summary of the state of fatherhood across cultures, classes, economic systems, and family formations. This classic guide offers a single-source reference for the most recent findings and beliefs related to fathers and fatherhood. This thoroughly updated new edition provides the latest material on topics such as: The effects of divorce Fathers from low-income backgrounds Stepfathers’ lives: exploring social context and interpersonal complexity Social policy Gay fathers Fatherhood and masculinity The definitive book on when, why, and how fathers matter to their children and families, The Role of the Father in Child Development, Fifth Edition is an essential reference for all mental health professionals who endeavor to understand and support fathers in becoming positive influences in their children’s development.
This volume presents a state-of-the-art debate on the controversial topic of development aid. The contributors are all experts in the field of international development. Presents some challenging conclusions about the role that aid plays in catalysing, or stifling, development. Represents a wide range of different analytical perspectives.
Protein kinases play a critical role in cellular processes that impact overall organismal health and function. Of the kinases that collectively make up the Human Kinome, CK2 has garnered special attention because of its significant role in the generation of the human phosphoproteome. The role CK2 plays in the development of cancer and other disease has also made it of significant interest for its potential role in future therapeutics. Protein Kinase CK2 comprehensively brings together the varied work being done on this critical enzyme. Protein Kinase CK2 is logically divided into three sections. The first section reviews key molecular and structural aspects of the enzyme. The second section looks at functional aspects of CK2 and the diverse roles it plays in cellular development, function, and health. The final section focuses on CK2 and cancer, looking at the impacts of the kinase on neoplastic development and its rapidly developing role as a therapeutic agent. With contributions from the world’s leading experts in the field, Protein Kinase CK2 will serve as an invaluable guide to the expanding and vibrant body of research being performed on this enzyme. This will be an essential volume for anyone working in the fields of biochemistry, protein science, signal transduction, metabolic regulation, and cancer biology and therapeutics. Editor Lorenzo A. Pinna is Professor in the Department of Biomedical Sciences at the University of Padua, Padua, Italy. Also Published in the Wiley-IUBMB Series on Biochemistry and Molecular Biology: Plant Phenolics and Human Health: Biochemistry, Nutrition, and Pharmacology Edited by Cesar G. Fraga ISBN: 978-0-470-28721-7
Полный вариант заголовка: «The rural economy of Yorkshire : Vol. 1 : comprising the management of landed estates, and the present practice of husbandry in the agricultural districts of that county : in 2 volumes / by Mr. Marshall».
An authoritative look at the application of chemical biology in drug discovery and development Based on the award-winning Wiley Encyclopedia of Chemical Biology published in 2008, this book explores the role of chemical biology in drug discovery and development. The first part of the book reviews key principles and techniques used in the design and evaluation of drug candidates. The second part elucidates biological mechanisms of certain diseases, illuminating approaches to investigate and target these diseases. Comprising carefully selected reprints from the Encyclopedia as well as new contributions from leading scholars in the field, this book provides researchers in academia and industry with important information to aid in the development of novel agents to treat disease. Self-contained articles cover a variety of essential topics, including: The design, development, and optimization of drug candidates The pharmacokinetics and properties of drugs Drug transport and delivery Natural products and natural product models as pharmaceuticals Biological mechanisms underlying health and disease Treatment strategies for a range of diseases, from HIV to schizophrenia Chemical Biology is a top-notch guide and reference for anyone working in the areas of drug discovery and development, including researchers in chemical biology and other fields such as biochemistry, medicine, and pharmaceutical sciences.
Wall bounded turbulent flows are of major importance in industrial and environmental fluid mechanics. The structure of the wall turbulence is intrinsically related to the coherent structures that play a fundamental role in the transport process. The comprehension of their regeneration mechanism is indispensable for the development of efficient strategies in terms of drag control and near wall turbulence management. This book provides an up-to-date overview on the progress made in this specific area in recent years.
This accessible guide to the development of Japan’s indigenous religion from ancient times to the present day offers an illuminating introduction to the myths, sites and rituals of kami worship, and their role in Shinto’s enduring religious identity. Offers a unique new approach to Shinto history that combines critical analysis with original research Examines key evolutionary moments in the long history of Shinto, including the Meiji Revolution of 1868, and provides the first critical history in English or Japanese of the Hie shrine, one of the most important in all Japan Traces the development of various shrines, myths, and rituals through history as uniquely diverse phenomena, exploring how and when they merged into the modern notion of Shinto that exists in Japan today Challenges the historic stereotype of Shinto as the unchanging, all-defining core of Japanese culture
This Task Force report reviews the evidence that the seeds of many adult diseases are sown in utero and in infancy. The report, written by experts in the field, summarises current knowledge in this area. It illustrates how early life nutrition can bring about changes in organ development and function, thus programming risk of disease in adult life. It also considers what might be done in early life to reduce the burden of future ill health. Nutrition and Development: Short- and Long-Term Consequences for Health includes chapters on the history of this topic area, normal growth and development, and current recommendations and practice in relation to nutrition and diet in early life. Chapters exploring the possible mechanisms and pathways of critical windows for development cover the effects of diet and nutrition in early life on organ and skeletal development, the role of sex hormones in programming disease susceptibility, the establishment of gastrointestinal microbiota, and the impact of early life nutrition on cognitive and neurological development. This new report: • describes how development occurs and explores how changes in the fetal and postnatal environment, such as over- or under-nutrition, can result in permanent alterations in function; • explains how diet and nutrition in early life can affect risk of adult disease, with specific chapters on allergic disease and asthma, bone health, cancer, cardiovascular disease, cognitive function, diabetes and obesity; • includes a summary of the key points, as well as recommendations in each chapter to help fill the gaps in our knowledge; • provides an overview of the main messages in a practical question and answer format suitable for lay readers. Nutrition and Development is an important information resource for those involved in research and teaching in the health sciences sector and is also of value to those involved in making decisions about health policy. It will be of interest to a broad range of health professionals, the food industry and those who write and broadcast about the effects of food on health.
Given current projections of population and household numbers, housing has become arguably the most important issue in planning. Likewise, planning raises arguably the most important long term issues in housing, given the environmental consequences of urban development and the use of the home."Homes, Cities and Neighbourhoods" documents the evolution of typical urban landscapes from 1900 to the present with an emphasis on contemporary issues and practice. In doing this, the book examines in detail: the role of planning in the light of different interpretations of social change; quantity and quality in housing production; urban design in relation to housing and residential areas; and finally, the management of neighbourhoods.This book is intended for all those interested in the interaction between planning, housing markets and the urban environment in Britain.
A consolidated and comprehensive reference on ligand-binding assays Ligand-binding assays (LBAs) stand as the cornerstone of support for definition of the pharmaco-kinetics and toxicokinetics of macromolecules, an area of burgeoning interest in the pharmaceutical industry. Yet, outside of the Crystal City Conference proceedings, little guidance has been available for LBA validation, particularly for assays used to support macromolecule drug development. Ligand-Binding Assays: Development, Validation, and Implementation in the Drug Development Arena answers that growing need, serving as a reference text discussing critical aspects of the development, validation, and implementation of ligand-binding assays in the drug development field. Ligand-Binding Assays covers essential topics related to ligand-binding assays, from pharmacokinetic studies, the development of LBAs, assay validation, statistical LBA aspects, and regulatory aspects, to software for LBAs and robotics and other emerging methodologies for LBAs. Highlights include: A general discussion of challenges and proven approaches in the development of ligand-binding assays More detailed examination of characteristics of these assays when applied to support of pharmacokinetic and toxicokinetic studies of compounds at different stages in the discovery or development timeline A concise, but detailed, discussion of validation of ligand-binding assays for macromolecules A practical approach to «fit-for-purpose» validation of assays for biomarkers, those molecules receiving increased attention as potentially demonstrating that the target chosen in discovery is being modulated by the candidate therapeutic, both in nonclinical and clinical studies Written by a team of world-recognized authorities in the field, Ligand-Binding Assays provides key information to a broad range of practitioners, both in the pharmaceutical and allied industries and in related contract research organizations and academic laboratories and, perhaps, even in the field of diagnostics and clinical chemistry.
Real Estate Development and Investment A Comprehensive Approach Written by real estate industry veteran Stephen Peca, this timely guide skillfully outlines the various phases of the real estate development process and addresses some of the most important issues associated with this discipline. Using numerous illustrations and anecdotes, this book takes you through the development process, from historical considerations and idea formulation to financial feasibility and asset disposition, while covering the entire cycle of real estate development for various property types. Topics touched upon throughout these pages include: The key factors affecting demand for different land uses and development The interaction of market research, financing, planning, contract negotiation, marketing, leasing, and property management The need for universal, current, and broad knowledge The importance of ethics in the development process The role of different professionals and companies involved in the development process Environmental considerations in real estate development And much more Filled with in-depth insights and practical advice, this reliable resource will help you gain a firm understanding of the functional skills necessary to be successful in this field and familiarize you with several often-overlooked-but essential aspects of commercial real estate development.
With the increasing importance of the role of China in the international political and economic arena, Chinese accounting has attracted more foreign attention. Foreign investment has increased and many joint ventures and foreign companies have been set up in China. With the growth of the economy and the opening up of the Chinese market, accounting systems in China have been changing. The purpose of this book is to examine major events and reforms which occurred in Chinese accounting within this transformation period and then to assess critically the impact of politics, the economy and culture on the development of Chinese accounting.
Developing Expertise in Critical Care Nursing examines the development of professional expertise in critical care nursing, based on extensive research in clinical practice. It offers a repertoire of learning and assessment methods that enable practitioners to grow their own expertise and foster developments in others. Developing Expertise in Critical Care Nursing will be of interest to practitioners who aspire to advanced level practice in critical care and to all who facilitate this process. It debates the characteristics of expert practice and practice development and examines the acquisition of core skills, and career development in critical care using a role transition model.