An essential introduction to conducting the various stages of medical device clinical trials Clinical research continues to be one of the most vital components of pharmaceutical, biostatistical, and medical studies. Design, Execution, and Management of Medical Device Clinical Trials provides a uniform methodology for conducting and managing clinical trials. Written in a style that is accessible to readers from diverse educational and professional backgrounds, this book provides an in-depth and broad overview for successfully performing clinical tasks and activities. Throughout the book, practical examples compiled from both the author's and other researchers' previous clinical trial experiences are discussed in a sequential manner as they occur in the study, starting from the development of the clinical protocol and the selection of clinical sites and ending with the completion of the final clinical study report. Next, readers are guided through the development of important clinical documents, including informed consent forms, case report forms, and study logs. A careful review of the Food and Drug Administration (FDA) and International Conference on Harmonisation (ICH) regulations applicable to medical devices is also featured. Additional coverage includes: Qualification and selection of investigators Study monitoring visits Definitions and reporting procedures for adverse events The use of biostatistical methodology in clinical research, including the use of biostatistics for sample size determination and study endpoints The roles and responsibilities of all members of a clinical research team The book concludes with an insightful discussion of special ethical conduct for human research and challenging issues to consider during the design of clinical studies. A glossary lists important clinical and statistical terms used in clinical research, and an extensive reference section provides additional resources for the most up-to-date literature on the topic. Design, Execution, and Management of Medical Device Clinical Trials is an excellent book for clinical research or epidemiology courses at the upper-undergraduate and graduate levels. It is also an indispensable reference for clinical research associates, clinical managers, clinical scientists, biostatisticians, pharmacologists, and any professional working in the field of clinical research who would like to better understand clinical research practices.
All you need to know on web design in a thorough new edition If you want just one complete reference on web design, this book is it. The newest edition of this essential guide features 650+ pages on the latest tools and new web design standards, such as HTML5, CSS 3, and other core technologies and page-building strategies. Five minibooks provide deep coverage: essential pre-design considerations, how to establish the look of your site, building a site, how to test your site, and taking your site public. Design professional and author Sue Jenkins understands what designers need and gives you the answers. Thorough revision brings you up to date on the latest changes in the world of web design Features five minibooks that cover all the bases: Getting Started, Designing for the Web, Building the Site, Standards and Testing, and Publishing and Site Maintenance Covers the latest tools, page-building strategies, and emerging technologies, such as HTML5 and CSS 3 Includes over 650 pages of detail on such topics as establishing audience focus, creating content, using mock-ups and storyboards to establish the look, how to design for text and images, testing your site, and more If you're looking for an in-depth reference on all aspects of designing and building a site and taking it live, Web Design All-in-One For Dummies, 2nd Edition is the book.
Following the huge success of the first edition, which has become THE reference source for everyone working in the field, this long-awaited, completely updated edition features almost 50% new content. The world-renowned chemist Prof Dennis Hall is joined by a select group of top authors to cover all modern aspects of boronic acid derivatives in one comprehensive handbook. The experimental procedures described make for extremely useful reading. From the reviews of the first edition: «…deserves to be on the bookshelf of all synthetic chemists, whether in discovery or process chemistry.»
The must-have manual to understand and use the latest edition of the Fifth Edition The professional standard in the field of project management, A Guide to the Project Management Body of Knowledge (PMBOK® Guide—Fifth Edition) published by the Project Management Institute (PMI®) serves as the ultimate resource for professionals and as a valuable studying and training device for students taking the PMP® Exam. A User's Manual to the PMBOK® Guide takes the next logical step to act as a true user's manual. With an accessible format and easy-to-understand language, it helps to not only distill essential information contained in the PMBOK® Guide—Fifth Edition, but also fills an educational gap by offering instruction on how to apply its various tools and techniques. This edition of the User's Manual: Defines each project management process in the PMBOK® Guide—Fifth Edition, describes the intent, and discusses the individual ITTOs (inputs, tools and techniques, and outputs) Features examples, handy tips, and sample forms to supplement learning Contains a data flow diagram of each process in the PMBOK® Guide—Fifth Edition to show how information is distributed Is updated to provide deeper coverage of stakeholder management and to include new processes for scope, schedule, cost, and stakeholder management The User's Manual enables you to put the PMBOK Guide—Fifth Edition to work on your projects. It will help you implement the processes described in the PMBOK Guide—Fifth Edition and apply the tools and techniques to help make your projects successful. Thorough in coverage and rich in content, it is a worthy companion to augment the important strategies laid out in the PMBOK® Guide—Fifth Edition, and the one book that aspiring or professional project managers should never be without. Fully updated to align with A Guide to the Project Management Body of Knowledge (PMBOK® Guide)–Fifth Edition Describes how to apply tools and techniques for projects and how to create process outputs Presents information by process group Expands upon the PMBOK® Guide with information on the sponsor's role and planning loops Integrates and describes interpersonal skills into the process where they are identified (PMBOK, PMI, PMP and Project Management Professional are registered marks of the Project Management Institute, Inc.)
Get ahead of the C++ curve to stay in the game C++ is the workhorse of programming languages and remains one of the most widely used programming languages today. It's cross-platform, multi-functional, and updates are typically open-source. The language itself is object-oriented, offering you the utmost control over data usage, interface, and resource allocation. If your job involves data, C++ proficiency makes you indispensable. C++ All-in-One For Dummies, 3rd Edition is your number-one handbook to C++ mastery. Author John Paul Mueller is a recognized authority in the computer industry, and your ultimate guide to C++. Mueller takes you through all things C++, including information relevant to the 2014 update. Learn how to work with objects and classes Conquer advanced programming and troubleshooting Discover how lambda expressions can make your code more concise and readable See Standard Library features, such as dynamic arrays, in action Online resources include source code from examples in the book as well as a C++ GNU compiler. If you need to learn C++, this is the fastest, most effective way to do it. C++ All-in-One For Dummies, 3rd Edition will get you up and running quickly, so you can get to work producing code faster and better than ever.
A highly accessible alternative approach to basic statistics Praise for the First Edition: «Certainly one of the most impressive little paperback 200-page introductory statistics books that I will ever see . . . it would make a good nightstand book for every statistician.»—Technometrics Written in a highly accessible style, Introduction to Statistics through Resampling Methods and R, Second Edition guides students in the understanding of descriptive statistics, estimation, hypothesis testing, and model building. The book emphasizes the discovery method, enabling readers to ascertain solutions on their own rather than simply copy answers or apply a formula by rote. The Second Edition utilizes the R programming language to simplify tedious computations, illustrate new concepts, and assist readers in completing exercises. The text facilitates quick learning through the use of: More than 250 exercises—with selected «hints»—scattered throughout to stimulate readers' thinking and to actively engage them in applying their newfound skills An increased focus on why a method is introduced Multiple explanations of basic concepts Real-life applications in a variety of disciplines Dozens of thought-provoking, problem-solving questions in the final chapter to assist readers in applying statistics to real-life applications Introduction to Statistics through Resampling Methods and R, Second Edition is an excellent resource for students and practitioners in the fields of agriculture, astrophysics, bacteriology, biology, botany, business, climatology, clinical trials, economics, education, epidemiology, genetics, geology, growth processes, hospital administration, law, manufacturing, marketing, medicine, mycology, physics, political science, psychology, social welfare, sports, and toxicology who want to master and learn to apply statistical methods.
Издание упаковано в картонный DigiPack размером 19 см х 14 см с 30-страничным буклетом-книгой, закрепленным в середине упаковки. Буклет содержит фотографии и дополнительную информацию на английском языке.
Joseph Conrad was a Polish-British writer regarded as one of the greatest novelists to write in the English language. Though he did not speak English fluently until his twenties, he was a master prose stylist who brought a non-English sensibility into English literature. He wrote stories and novels, many with a nautical setting, that depict trials of the human spirit in the midst of an impassive, inscrutable universe.
The One Essence, 40 мл
The One Eau de Toilette
Updated version of the bestselling 3ds Max book on the market Autodesk 3ds Max is top animation software used by developers, visual effects artists, and graphic designers in film, television, and the game industry. One place designers turn for crucial information on how to use 3ds Max is this in-depth book. Whether you're a beginner just itching to create something right away or an experienced user checking out the latest and greatest features, you'll find it here. See what's new, what's tried and true, and just how creative you can get using the tips, tricks, and techniques in this essential reference. Every previous edition has been a top-seller. Packs expert advice, timesaving tips, and more than 150 step-by-step tutorials into over 800 pages that help you master this complex software Gives you in-depth coverage of all new features, as well as the basics Jump-starts your learning on day one with a Quick Start tutorial, so you can create an exciting animation right away Provides you with access to all before-and-after example files from each tutorial, plus unique models and textures that you can customize on the companion CD Includes extra content from previous editions of the 3ds Max Bible, including bonus Quick Start tutorials from previous editions Whether you're just starting out or getting up to speed on 3ds Max 2013, this comprehensive book will get you there.
The One Essence, 65 мл